Neurologic Manifestations Associated with Parvovirus B19 Infection

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Neurologic manifestations associated with parvovirus B19 infection.

Eighty-one cases of neurologic disease, including encephalitis, meningitis, stroke, and peripheral neuropathy, that were associated with parvovirus B19 infection were reviewed. Most patients were children, and two-thirds had central nervous system manifestations. One-third had altered immunity. Viral symptoms (odds ratio [OR], 5.7; P= .002), rash (OR, 11.5; P< .001), and peripheral nervous syst...

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Aplastic anaemia associated with parvovirus B19 infection.

Parvovirus B19 involvement was investigated in 30 children with severe aplastic anaemia. Active or recent parvovirus B19 infection, as shown by B19 DNA viraemia, positive B19 specific IgM antibodies, or both, was diagnosed in six patients. There were no other plausible causes. We suggest that parvovirus B19 infection might be associated with severe aplastic anaemia.

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Hepatitis Associated with Acute Parvovirus B19 Infection

alovirus, and human herpes virus 6; HIV 1 and HIV 2; and Still’s Disease, Severe Thrombocytopenia, and Acute hepatitis A, B, C, and G viruses. The negative serologies were Hepatitis Associated with Acute Parvovirus B19 Infection also confirmed by use of PCR. ELISA for antibodies to B19 showed positivity for B19 IgG The pathogenetic role of human parvovirus B19 infection in and negativity for B1...

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Isolated velopalatine paralysis associated with parvovirus B19 infection.

A case of isolated velopalatine paralysis in an 8-year-old boy is presented. The symptoms were sudden-onset of nasal speech, regurgitation of liquids into the nose and dysphagia. Brain MRI and cerebrospinal fluid examination were normal. Infectious serologies disclosed an antibody arrangement towards parvovirus B19 that was typical of recent infection. In the absence of other positive data, the...

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Cytokine gene polymorphisms associated with symptomatic parvovirus B19 infection.

BACKGROUND The immune system has been implicated in the pathogenesis of certain clinical manifestations of parvovirus B19 infection, including rash and arthralgia. Cytokines feature in the pathogenesis of parvovirus B19 infection, so inherited variability in cytokine responses to B19 infection might have a bearing on the symptomatology of parvovirus B19 infection. AIMS To investigate the poss...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2009

ISSN: 1058-4838,1537-6591

DOI: 10.1086/599042